Our Science

Our Ground-breaking Sleep Study

We're excited to announce the successful completion of our pioneering clinical trial for Defined Sleep. The results demonstrated Defined Sleep increased restorative sleep and were presented at the Sleep 2023 conference, a joint meeting of the American Academy of Sleep Medicine and the Sleep Research Society.
Our human trial of Defined Sleep is the first double-blind, placebo-controlled trial of any CBD-based sleep aid. This study represents a landmark step in understanding CBD’s effects on human restorative sleep. Visit ClinicalTrials.gov for in-depth information on our work.

ClinicalTrials.gov

Details about our pioneering human trial.

Our Human Sleep Trial

125 Participants

Study participants were insomnia-suffering adults from across the U.S.

 

Comprehensive Data

Objective data was captured with wearable devices. Subjective data was collected via participant surveys.

IRB Approved

Our study was approved by an Institutional Review Board, in accordance with FDA regulations.


Trial participants consisted of ~125 insomnia-suffering adults selected from across the United States. Objective sleep data was collected via wearable technology. Subjective feedback was obtained via participant surveys. Importantly, the clinical trial was approved by an Institutional Review Board (IRB), which ensured the human study was governed in accordance with FDA regulations and can be published in peer-reviewed scientific journals.


The manuscript detailing our clinical trial is available upon request by emailing us at info@definedresearch.com.

Product Purity

At Defined Research, we’re committed to delivering the highest level of formula purity in all of our ingredients. We’ve spent years carefully selecting and testing everything that goes into our product, and we lab-test every batch before it’s bottled. The result is that every batch of Defined Sleep contains the same, precise concentrations of active ingredients – consistently resulting in a better night’s sleep.


This rigorous approach is different than most CBD sleep products which are composed of extracts from hemp plants. The problem, for consumers, is that the specific contents of every extract can dramatically vary from batch to batch – just like wines from the same vineyard taste different each year.

Sleep & Beyond

Creating a solution for insomnia is just the first step in our scientific exploration of CBD’s wellness capabilities. We’re committed to discovering CBD formulas that provide valid pharmaceutical alternatives for a wide range of chronic human conditions. In addition to insomnia, we believe CBD promises substantial therapeutic benefits for anxiety, pain, arousal, inflammation and more. These will be the focus of our journey as we continue to expand our science.

Product Testing

Every lot of Defined Sleep is tested to the highest safety and quality standards. We use CBD isolate that is 99.9% pure to ensure each batch is exactly the same and has 0.0% THC. Our CBD isolate is from a GMP certified manufacturer using Colorado grown hemp.


Our third party testing is done at an ISO/IEC 17025:2005 accredited laboratory and recognized by the United States Food and Drug Administration (FDA) lab. All of our products are tested for Potency, Terpenes, Pesticides, Heavy Metals, Residual Solvents, Foreign Materials and Bacteria.